BIOLEAN Free® (Wellness International)
Herbal & Amino Acid Dietary Supplement

Thermogenesis refers to the body's ability to convert substrates such as proteins, fats and carbohydrates into heat energy. This is carried out most efficiently in the Brown Adipose Tissue of our body which uses fatty acids as its preferred fuel. Other fat cells, namely White Adipose Tissue, are concerned primarily with the storage of fat rather than its conversion to energy. The thermogenic pathway is complex and relies upon a series of reactions to occur. BIOLEAN Free utilizes many compounds which act at various locations in this pathway to ensure the maximum efficiency of the thermogenic process. Quebracho is one of these very special compounds. This South American plant contains quebrachine, aspidiospermine and other alkaloids that possess the ability to block alpha-2 adrenergic receptors in the body. This produces an enhanced sympathetic nervous system effect which, in turn, increases lipolysis (fat breakdown) within fat cells. The fatty acids released by this process can then be transported into the mitochondria to be used as a fuel. Ginger, cinnamon, horseradish, turmeric, cayenne and mustard are spices that stimulate thermogenesis in different ways. Some stimulate lipid mobilization in adipose tissue; others raise the resting metabolic rate; and some increase cAMP levels by inducing more beta receptors on fat cells and by increasing the concentration of adenylate cyclase. cAMP increases the breakdown of triglycerides to free fatty acids which are later used as fuel by the mitochondria in the cell. Methylxanthines (such as those found in green tea and yerba maté) also increase cAMP levels, but do this by inhibiting the enzyme, phosphodiesterase. These compounds have been noted to increase mental alertness, improve vitality, satisfy the appetite and increase energy. In addition to its methylxanthine content, green tea has recently been shown to possess strong antioxidant properties. Yerba maté is a plant that has been shown to produce the positive effects above without causing the insomnia seen with other methylxanthine-containing plants (such as coffee and kola nut). BIOLEAN Free also contains vitamin B-3 (niacin), vitamin B-6 (pyridoxine), chromium and vanadium, which aid in the proper metabolism of fats, proteins and carbohydrates. L-tyrosine also aids in metabolism and promotes satiety through hypothalamic release of CCK. Methionine is a precursor of L-carnitine which aids in the transport of fatty acids into the mitochondria for thermogenesis. Other herbs have been utilized in BIOLEAN Free. Ginseng and ho shou wu possess adaptogenic properties. Adaptogens help the body adapt to physiological and environmental stresses. Ginseng accomplishes this through its stabilizing effect on the hypothalamic-pituitary-adrenal-sympathetic nervous system. It can mediate an increased adrenal response to stress.

Ho shou wu has a stabilizing effect on the endocrine system and has restorative properties. It is also an antioxidant with a high flavonoid content. Centella asiatica contains asiaticoside and has been shown to increase activity levels and ease the body's ability to overcome fatigue when taken with ginseng and cayenne. Individually, centella has been shown to increase memory and mental acuity in studies abroad. Uva ursi contains the glycoside arbutin and promotes urinary health and body strength through its purifying effects. Ginkgo biloba is a tree whose leaves have been used for centuries as an herbal medicine. It contains flavonoids and is therefore a strong antioxidant. It reduces the tendency of platelets to stick together by inhibiting Platelet Activating Factor. It has been shown to increase blood flow to the heart, brain and other organs.

Directions: Adults (18 years and older) may take 4 tablets in the mid to late morning with a low-calorie food. Needs may vary with each individual. Some persons may require less than 4 caplets, or may prefer taking 3 tablets mid morning and 1 additional tablet mid afternoon to achieve optimum results. Do not exceed recommended daily amounts. It is recommended that you drink at least eight glasses of water daily.

Warnings: Not for use by children, pregnant women or lactating women. Consult your physician before using this product if you are taking appetite suppressing drugs or cardiovascular medication. Consult your physician if you have hypertension, heart disease, arrhythmias, prostatic hypertrophy, glaucoma, liver disease, renal disease or diabetes. Do not use if you have hyperthyroidism, psychosis, Parkinson's Disease, or are taking Monoamine oxidase inhibitors. BIOLEAN Free should not be taken on the same day as original BIOLEAN®. It is recommended that you minimize your caffeine intake while consuming this product. If allergic symptoms develop, discontinue use. Store in a cool, dry place. Keep out of reach of children